


γδ T-Cells in
Chronic Myeloid Leukemia

γδ T-Cells in Endometriosis
γδ T-Cells in Multiple Myeloma








γδ T-Cells in Glioblastoma
γδ T-Cells in Multiple Myeloma
γδ T-Cells in
CMV reactivation

The NFkB activation domain is 14-amino-acid-long variant of the 9aaTAD
Houser J, Jendruchova K, Knight A and Piskacek M
Biochemical Journal (2023) doi.org/10.1042/BCJ20220605
Knight A, Piskacek M, Jurajda M, Prochazkova J, Racil Z, Zackova D, Mayer J
Cancer Immunology, Immunotherapy (2022) doi.org/10.1007/s00262-022-03312-3
Cryptic inhibitory regions nearby activation domains
Knight A and Piskacek M
Biochimie (2022) doi.org/10.1016/j.biochi.2022.05.004
Hudecek R, Kohlova B, Siskova I, Piskacek M, Knight A
Frontiers in Immunology (2021) doi.org/10.3389/fimmu.2021.752646
Plasmacytoid dendritic cells in patients with MGUS and Multiple Myeloma
Knight A, Rihova L, Kralova R, Penka M, Adam Z, Pour L, Piskacek M and Hajek R
Journal of Clinical Medicine (2021) doi.org/10.3390/jcm10163717
The 9aaTAD activation domains in the four Yamanaka Oct4, Sox2, Myc, and Klf4 transcription factors
Piskacek M, Otasevic T, Repko M, Knight A
Stem Cell Rev and Rep (2021) doi.org/10.1007/s12015-021-10225-8
Full version on www.biorxiv.org/content/10.1101/2019.12.15.876706v1.full.pdf
Universal two-point interaction of mediator KIX with 9aaTAD activation domains
Hofrova A, Lousa P, Kubickova M, Hritz J, Otasevic T, Repko M, Knight A and Piskacek M
Journal of Cellular Biochemistry (2021) doi.org/10.1002/jcb.30075
Piskacek M, Havelka M, Jendruchova K, Knight A, Keegan LP
Cellular and Molecular Life Sciences (2019) doi.org/10.1007/s00018-019-03251-w
Nuclear Hormone Receptors: ancient 9aaTAD and evolutionally gained NCoA Activation Pathways
Piskacek M, Havelka M, Jendruchova K, Knight A
Journal of Steroid Biochemistry and Molecular Biology (2018) doi.org/10.1016/j.jsbmb.2018.11.008
The 9aaTAD is exclusive activation domain in Gal4
Piskacek M, Havelka M, Rezacova M, Knight A
PlosOne (2017) doi.org/10.1371/journal.pone.0169261
Gal4 activation domain 9aaTAD could be inactivated by adjacent mini-inhibitory domain
and reactivated by distal re-activation domain
Piskacek M, Havelka M, Rezacova M, Knight A
BioRxiv (2017) doi.org/10.1101/110882
The 9aaTAD Transactivation Domains: from Gal4 to p53
Piskacek M, Havelka M, Rezacova M, Knight A
PlosOne (2016) doi.org/10.1371/journal.pone.0162842
Shared structural features of the 9aaTAD family in complex with CBP
Piskacek M, Vasku A, Hajek R and Knight A
Molecular BioSystems (2014) doi.org/10.1039/c4mb00672k
CMV-independent lysis of glioblastoma by ex vivo expanded/activated Vδ1+ γδ T cells.
Knight A, Arnouk H, Britt W, Gillespie GY, Cloud GA, Harkins L, Su Y, Lowdell MW, Lamb LS
PLoS One (2013) doi.org/journal.pone.0068729
Knight A, Mackinnon S, Lowdell MW
Cytotherapy (2012) doi.org/10.3109/14653249.2012.700766
Knight A, Madrigal AJ, Grace S, Sivakumaran J, Kottaridis P, Mackinnon S, Travers PJ, Lowdell MW
Blood (2010) doi.org/10.1182/blood-2010-01-255166
Rsp5 promotes Gene Activation mediated by 9aaTAD Transcription Factors Oaf1 and Gal4
Lipp J, Koranda M, Piskacek M
Nature Precedings (2009) doi.org/10.1038/npre.2009.3968.1
A novel 9-amino-acid transactivation domain in the C-terminal part of Sox18
Sandholzer J, Hoeth M, Piskacek M, Mayer H, de Martin R
Biochem Biophys Res Commun (2007) doi.org/10.1016/j.bbrc.2007.06.095
9aaTAD Prediction result (2006)
Piskacek M
Nature Precedings (2009) doi.org/10.1038/npre.2009.3984.1
Nine-amino-acid transactivation domain: Establishment and prediction utilities
Piskacek S, Gregor M, Nemethova M, Grabner M, Kovarik P, Piskacek M
Genomics (2007) doi.org/10.1016/j.ygeno.2007.02.003
Functional analysis of the Zn(2)Cys(6) transcription factors Oaf1p and Pip2p
Baumgartner U, Hamilton B, Piskacek M, Ruis H, Rottensteiner H
J Biol Chem (1999) doi.org/10.1074/jbc.274.32.22208
Collaboration:
Predicting the function and subcellular location of Caenorhabditis elegans proteins
Gurvitz A, Langer S, Piskacek M, Hamilton B, Ruis H, Hartig A
Yeast (2000) doi.org/10.1002/1097-0061(20000930)17:3<188::AID-YEA27>3.0.CO;2-E
Conditional Knock-down of the Mitochondrial Magnesium Channel hMrs2
Piskacek M, Zotova L, Zsurka G and Schweyen RJ
Journal of Cellular and Molecular Medicine (2009) doi.org/10.1111/j.1582-4934.2008.00328.x
Functionally suppressive CD8 T regulatory cells are increased in patients
with multiple myeloma: a cause for immune impairment
Muthu Raja KR, Kubiczkova L, Rihova L, Piskacek M, Vsianska P, Hezova R, Pour L, Hajek R
PLoS One (2012) doi.org/10.1371/journal.pone.0049446
Do human B-lymphocytes avoid aging until 60 years?
Knight A, Nemec P, Bretzova S, Valkova L, Kolmanova K, Vytopilova R, Havelka M,
Vsianska P, Rihova L, Krejci M and Piskacek M
Oncotarget (2016) doi.org/10.18632/oncotarget.10146
Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M,
Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P.
Sci Signal (2018) doi.org/10.1126/scisignal.aap8608
Hribkova H, Svoboda O, Bartecku E, Zelinkova J, Horinkova J, Lacinova L, Piskacek M, Lipovy B, Provaznik I, Glover JC, Kasparek T, Sun YM.
Front Cell Neurosci. (2022) doi: 10.3389/fncel.2022.830757